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硼替佐米雜質(zhì)有哪些
  • 更新日期：2023-10-11      瀏覽次數(shù)：381

      • 東莞市景源實驗科技有限公司可提供硼替佐米雜質(zhì)全套，并隨貨提供COA證書，HPLC，NMR，MS圖譜，10mg/25mg/50mg/100mg/500mg等多種規(guī)格可選，更大規(guī)格需確認庫存。我司可根據(jù)客戶需要提供硼替佐米雜質(zhì)定制服務(wù)。


      硼替佐米的相關(guān)介紹

      硼替佐米（Bortezomib），為黃色固體的化學品，商品名 ：萬珂® VELCADE®，中文別名：MG-341;硼替佐米雜質(zhì);保特佐米，熔點：122-124°C，分子式 :C19H25BN4O4，分子量 :384.23700，用于既往未經(jīng)治療的且不適合大劑量化療和骨髓抑制的多發(fā)性骨髓瘤患者的治療；或單藥用于至少接受過一種或一種以上治療后復發(fā)的多發(fā)性骨髓瘤患者的治療；本品可用于復發(fā)或難治性套細胞淋巴瘤患者的治療，此患者在使用本品前至少接受過一種治療。用于該適應(yīng)癥的安全有效性數(shù)據(jù)來自國外一項針對既往治療后復發(fā)的套細胞淋巴瘤的單臂Ⅱ期臨床研究，尚缺乏針對中國人群的臨床研究數(shù)據(jù)。


      硼替佐米雜質(zhì)有哪些


      中文名稱

      英文名稱

      CAS號

      硼替佐米標準品

      Bortezomib

      179324-69-7

      硼替佐米雜質(zhì)1

      Bortezomib Amide Analog

      289472-80-6

      硼替佐米雜質(zhì)2

      Bortezomib Acid Analog

      114457-94-2

      硼替佐米雜質(zhì)3

      Bortezomib (2R)-Acid

      1608986-16-8

      硼替佐米雜質(zhì)4

      Desisobutyl-n-butyl Bortezomib

      1104011-35-9

      硼替佐米雜質(zhì)5

      (1R, 2R)-Bortezomib

      1132709-15-9

      硼替佐米雜質(zhì)6

      (1S, 2S)-Bortezomib

      1132709-14-8

      硼替佐米雜質(zhì)7

      (1S, 2R)-Bortezomib

      1132709-16-0

      硼替佐米雜質(zhì)8

      PS-619


      硼替佐米雜質(zhì)9

      Bortezomib Hydroxy (1R, 2S)-Isomer,(R)-Hydroxy Des(boric Acid) Bortezomib

      289472-78-2

      硼替佐米雜質(zhì)10

      Bortezomib Hydroxy (1R, 2R)-Isomer,(R,R)-Hydroxy Des(boric Acid) Bortezomib


      硼替佐米雜質(zhì)11

      Bortezomib Hydroxy (1S, 2S)-Isomer,(R)-Hydroxy Des(boric Acid) Bortezomib

      289472-81-7

      硼替佐米雜質(zhì)12

      Bortezomib Acid Methyl Ester

      73058-37-4

      硼替佐米雜質(zhì)13

      Bortezomib Pinanediol Impurity,(1R)-(S)-Pinanediol-N-(2-pyrazinylcarbonyl)-L-phenylalanine-L-leucine boronate

      205393-22-2

      硼替佐米雜質(zhì)14

      Bortezomib Impurity N,(R)-Hydroperoxy Des(boric Acid) Bortezomib,Bortezomib R-Hydroxyperoxide

      886979-78-8

      硼替佐米雜質(zhì)15

      Bortezomib Impurity M,(S)-Hydroperoxy Des(boric Acid) Bortezomib,Bortezomib R-Hydroxyperoxide

      886979-81-3

      硼替佐米雜質(zhì)16

      N-((S)-1-(((S)-1-methoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


      硼替佐米雜質(zhì)17

      N-((S)-1-(((S)-1-methoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


      硼替佐米雜質(zhì)18

      (S)-N-(1-(isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

      1446194-56-4

      硼替佐米雜質(zhì)19

      (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


      硼替佐米雜質(zhì)20

      (S)-N-(1-formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


      硼替佐米雜質(zhì)21

      3-Hydroxy Bortezomib


      硼替佐米雜質(zhì)22

      Bortezomib N-Hexyl Impurity,Desisobutyl-n-pentyl Bortezomib


      硼替佐米雜質(zhì)23

      Bortezomib L-Phenylalanyl Analog,L-Phenylalanine-bortezomib

      1194235-41-0

      硼替佐米雜質(zhì)24

      Bortezomib D-Phenylalanyl Analog,D-Phenylalanine-bortezomib